A New Generation Beyond CO2 or Erbium

"Pearl Fractional produces excellent results in a single treatment, even in the most difficult-to-treat areas, such as the upper lip. With YSGG’s optimal ratio of ablation and coagulation, deep fractional ablative treatments are not only effective, but my patients are delighted with only 5 days of downtime."
David J. Goldberg, M.D., Dermatologist
Pearl Fractional’s deep ablation and controlled thermal zone delivers maximum single-treatment results with superior patient comfort and minimal downtime.
- Indicated for moderate to severe photoaging.
- The 2790 nm wavelength (YSGG) controls thermal damage to maximize ablation while maintaining thermal stimulation and coagulation.
- Controlled thermal zone minimizes risk of PIH and other complications.
- Single treatment results are possible because our large 300 micron spot size ablates enough tissue in one pass.
- Wound healing causes increased fibroblast activity and long term collagen deposition. Improvement is realized over six month period.
- A recent comparative study to other fractional devices demonstrated that Pearl Fractional was a more comfortable patient experience; further, the treatment is possible with only topical anesthetics and/or local nerve blocks.

Immediate post-treatment histology* – 160 mJ
- Deep ablation: user-selectable up to >1 mm
- Coagulation on the edges (~40 µm) provides hemostatis
- Balance of ablation and coagulation optimizes tissue removal to safely improve or eliminate photoaging and other dermal imperfections

Day 4 histology – 160 mJ
- Rapid healing and recovery due to epidermal migration from healthy tissue
- Consolidation of coagulated zone
- Full re-epithelialization is demonstrated by day four
Product Specifications
| Wavelength |
2790 nm (2.79 µm) |
| Energy |
60-320 mJ per microspot |
| Spot size |
300 microns |
| Scan size |
10 mm x 14 mm |
| Pulse width |
600 microseconds |
| Scanner |
Variable densities and patterns |
Clinical Papers
In Vivo Histological Evaluation of a Novel YSGG Ablative Fractional Device for Cutaneous Remodeling
Walfre Franco, PhD, Brian D. Zelickson, MD, Victor E. Ross, MD
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Learn More about Pearl Fractional
Pearl Fractional is part of the Fractional + Ablative Solution.
Contact your Cutera representative by email or call 1-888-428-8372.
On Demand Webinars
Pearl Fusion
presented by Brian S. Biesman, MD
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Introducing Pearl Fusion: Optimizing Ablative Results
presented by Jaggi Rao, MD
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Pearl Fractional Roundtable
presented by Brian Biesman, MD, Barry DiBernardo, MD, FACS and E. Victor Ross, MD
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